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ORIGINAL ARTICLE
Year : 2018  |  Volume : 7  |  Issue : 4  |  Page : 151-154

Association of in-vitro fertilization twin pregnancy with maternal and perinatal complications


1 Faculty of Medicine, Riga Stradiņš University, Riga, Latvia
2 Scientific Laboratory of Molecular Genetics, Riga Stradiņš University, Riga, Latvia
3 Department of Obstetrics and Gynecology, Riga Stradiņš University; Riga Maternity Hospital, Riga, Latvia

Correspondence Address:
Grasmane Adele
Faculty of Medicine, Riga Stradiņš University, Riga
Latvia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2305-0500.237051

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Objective: To analyze maternal and perinatal complication rates in in-vitro fertilization (IVF) twins and spontaneous twin pregnancies. Methods: The information on obstetric and perinatal outcomes and complications covering 95 IVF twins and 165 spontaneous twin pregnancies was collected from the medical records of Riga Maternity Hospital. Statistical analysis and adjustment for confounders was performed using the SPSS v24.0 software. The continuous data were compared using the t-test and Mann-Whitney U test for parametrical and non-parametrical data accordingly. The nominal data were analyzed using Pearson’s Chi-square test and Fisher’s exact test. Results: The preterm labor risk, intrauterine growth restriction, fetus weight between IVF and spontaneous twins were not statistically significant (P>0.005). At the same time our study revealed a statistically significant association of gestational diabetes and pregnancy induced hypertension with IVF twin pregnancies (P=0.025 and P=0.003, respectively). Moreover, IVF twins had higher odds to be delivered by cesarean section (P=0.001). Conclusions: IVF twin pregnancies are associated with a higher risk of development of gestational diabetes and gestational hypertension than spontaneous twin pregnancies.


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